Lintlha tse akaretsang
Alpha-fetoprotein (AFP) e khetholloa e le setho sa alpha-albuminoid gene superfamily e nang le albumin, AFP, vithamine D (Gc) protheine le alpha-albumin.AFP ke glycoprotein ea 591 amino acid le karolo ea carbohydrate.AFP ke e 'ngoe ea liprotheine tse khethehileng tse embryo 'me ke protheine ea serum e hlahelletseng qalong ea bophelo ba embryonic ea motho joalo ka khoeli e le' ngoe, ha albumin le transferrin li le teng ka bongata bo fokolang.E qala ho etsoa ka har'a motho ka mokotla oa yolk le sebete (likhoeli tse 1-2) mme haholo-holo sebeteng.Palo e nyane ea AFP e hlahisoa ke pampitšana ea GI ea mohopolo oa motho.Ho 'nile ha pakoa hore AFP e ka' na ea hlaha hape ka serum ka tekanyo e phahameng bophelong ba batho ba baholo ka ho kopana le mekhoa e tloaelehileng ea ho tsosolosa le ka khōlo e mpe.Alpha-fetoprotein (AFP) ke letšoao le ikhethileng bakeng sa lefu la sebete la hepatocellular carcinoma (HCC), teratoblastomas, le neural tube defect (NTD).
Keletso ea para | CLIA (Tlhapa-Tshireletso): 3C8-6 ~ 11D1-2 8A3-7 ~ 11D1-2 |
Bohloeki | >95%, e khethoa ke SDS-PAGE |
Tlhahiso ea Buffer | PBS, pH7.4. |
Polokelo | E boloke tlas'a maemo a nyopa ho -20℃ho ea ho -80℃ha o amohela. Khothalletsa ho aliquot protheine ka bongata bo nyane bakeng sa polokelo e nepahetseng. |
Lebitso la Sehlahiswa | Katse.Che | ID ea Clone |
AFP | AB0069-1 | 11D1-2 |
AB0069-2 | 3C8-6 | |
AB0069-3 | 8A3-7 |
Tlhokomeliso: Li-bioantibody li ka ikamahanya le maemo ho latela tlhoko ea hau.
1.Mizejewski GJ.(2001) Sebopeho le Mosebetsi oa Alpha-fetoprotein: Tšebelisano ho Li-Isoforms, Epitopes, le Conformational Variants.Exp Biol Med.226(5): 377-408.
2.Tomasi TB, le ba bang.(1977) Sebopeho le Mosebetsi oa Alpha-Fetoprotein.Tlhahlobo ea Selemo le Selemo ea Meriana.28:453-65 .
3.Leguy MC, le ba bang.(2011) Tlhahlobo ea AFP ka amniotic fluid: papiso ea mekhoa e meraro e ikemetseng.Ann Biol Clin.69(4): 441-6.