Lintlha tse akaretsang
Flu, kapa ntaramane, ke tšoaetso ea phefumoloho e tšoaetsanoang e bakoang ke mefuta e fapaneng ea livaerase tsa ntaramane.Matšoao a ntaramane a akarelletsa ho opa ha mesifa le ho opeloa ke mesifa, hlooho e opang, le feberu.Kokoana-hloko ea feberu ea mofuta oa A e lula e fetoha 'me ka kakaretso e ikarabella bakeng sa seoa se seholo sa ntaramane.
Influenza A e ka arolwa ka mefuta e menyenyane e fapaneng ho ya ka motswako wa diprotheine tse pedi hodima kokoana-hloko: hemagglutinin (H) le neuraminidase (N).
Keletso ea para | IC(Tlhokomelo-Tlhahiso):1B5-6 ~ 3A9-8 |
Bohloeki | >95%, e khethoa ke SDS-PAGE |
Tlhahiso ea Buffer | PBS, pH7.4. |
Polokelo | E boloke tlas'a maemo a nyopa ho -20℃ho ea ho -80℃ha o amohela. Khothalletsa ho aliquot protheine ka bongata bo nyane bakeng sa polokelo e nepahetseng. |
Lebitso la Sehlahiswa | Katse.Che | ID ea Clone |
Lefuba A | AB0023-1 | 1F10-1 |
AB0023-2 | 1B5-6 | |
AB0023-3 | 3A9-8 |
Tlhokomeliso: Li-bioantibody li ka ikamahanya le maemo ho latela tlhoko ea hau.
1.Senne DA , Panigrahy B , Kawaoka Y , et al.Patlisiso ea tatelano ea sebaka sa hemagglutinin (HA) sa tatellano ea livaerase tsa mokakallane oa H5 le H7: tatellano ea asiti ea amino sebakeng sa HA cleavage e le lets'oao la bokhoni ba pathogenicity.[J].Mafu a Avian, 1996, 40 (2): 425-437.
2.Benton DJ , Gamblin SJ , Rosenthal PB , et al.Phetoho ea sebopeho ho influenza haemagglutinin at membrane fusion pH[J].Tlhaho, 2020:1-4.
3.1.Urai C, Wanpen C. Evolution of Therapeutic Antibodies, Influenza Virus Biology, Influenza, le Influenza Immunotherapy.Biomed Res Int.2018.
4.2.Florian K. Karabelo ea 'mele oa motho ho tšoaetso ea kokoana-hloko ea ntaramane A le ente.Tlhaho e hlahloba immunology.2019, 19, 383-397.