Anti-human RBP4 Antibody, Mouse Monoclonal
Lintlha tsa sehlahisoa
Lintlha tse akaretsang
Retinol-binding protein 4 (RBP4) ke eona e tsamaisang retinol (eo hape e tsejoang e le vithamine A), 'me e ikarabella bakeng sa phetoho ea retinol e sa tsitsang le e sa tsitsang ka tharollo e nang le metsi hore e be e tsitsitseng le e qhibilihang ka har'a plasma ka ho kopana ha bona ka thata.Joaloka setho sa lipocalin superfamily, RBP4 e nang le sebopeho sa β-barrel se nang le sekoti se hlalositsoeng hantle se patoa ho tloha sebeteng, 'me ka lehlakoreng le leng se fana ka retinol ho tloha mabenkeleng a sebete ho ea ho lisele tsa peripheral.Ho plasma, RBP4-retinol complex e sebelisana le transthyretin (TTR), 'me tlamahano ena ke ea bohlokoa bakeng sa ho thibela ho tsoa ha RBP4 ka liphio glomeruli.RBP4 e hlahisoang ho tsoa mohloling oa ectopic e fana ka retinol hantle mahlong, 'me khaello ea eona e ama pono ea bosiu haholo.Haufinyane tjena, RBP4 e le adipokine, e fumanoa e hlahisoa ka lisele tsa adipose 'me e amana le botenya, insulin resistance (IR) le mofuta oa 2 lefu la tsoekere (T2DM).
Thepa
| Keletso ea para | CLIA (Tlhapa-Tshireletso): 9D11-8 ~ 3D4-1 3C8-1 ~ 3D4-1 |
| Bohloeki | >95% joalo ka ha ho khethoa ke SDS-PAGE. |
| Tlhahiso ea Buffer | PBS, pH7.4. |
| Polokelo | E boloke tlas'a maemo a nyopa ho -20 ℃ ho -80 ℃ ha e amoheloa. Khothalletsa ho aliquot protheine ka bongata bo nyane bakeng sa polokelo e nepahetseng. |
Papiso ea Tlholisano
Lintlha tsa Odara
| Lebitso la Sehlahiswa | Katse.Che | ID ea Clone |
| RBP4 | AB0032-1 | 9D11-8 |
| AB0032-2 | 3C8-1 | |
| AB0032-3 | 3D4-1 | |
| AB0032-4 | 1C6-1 |
Tlhokomeliso: Li-bioantibody li ka ikamahanya le maemo ho latela tlhoko ea hau.
Litlhaloso
1.Aiwei YB , Vijayalakshmi V , Bodles AM , et al.Retinol e tlamang protheine ea 4 ho batho: kamano le insulin ho hanyetsa, ho ruruha, le karabelo ho pioglitazone.[J].J Clin Endocrinol Metab (7): 2590-2597.
2.Haider DG , Karin S , Gerhard P , et al.Serum retinol- tlamang protheine ea 4 e fokotsehile ka mor'a ho lahleheloa ke boima ba 'mele ho batho ba batenya haholo.[J].Journal of Clinical Endocrinology & Metabolism (3): 1168-71.
