Anti-human PGI Antibody, Mouse Monoclonal
Lintlha tsa sehlahisoa
Lintlha tse akaretsang
Pepsinogen I, li-precursors tsa pepsin, e hlahisoa ke mucosa ea gastric mme e lokolloa ka har'a lumen ea gastric le potoloho ea peripheral.Pepsinogen e na le ketane e le 'ngoe ea polypeptide ea 375 amino acid e boima ba molek'hule ea 42 kD.PG I (isoenzyme 1-5) e patoa haholo-holo ke lisele tse ka sehloohong ka har'a fundic mucosa, athe PG II (isoenzyme 6-7) e hlahisoa ke litšoelesa tsa pyloric le proximal duodenal mucosa.
Precursor e bonahatsa palo ea lisele tse ka holim'a mpa hammoho le lisele tsa glandular, 'me e shebella atrophy ea gastric ka tsela e sa tobang.Li boetse li tsitsitse ka mokhoa o sa tloaelehang hobane li etsa mesebetsi ea tsona tlas'a maemo a thata a teng tsamaisong ea tšilo ea lijo.The atrophy of the corpus mucosa e lebisa ho tlase synthesis ea pepsinogen I mme ka hona e lokolloa ka tlase ho serum.Serum pepsinogen I e bontša mosebetsi le maemo a mucosa ea ka mpeng.
Thepa
| Keletso ea para | CLIA (Tlhapa-Tshireletso): 1C1-3 ~ 1G7-3 1E3-1 ~ 1G7-3 |
| Bohloeki | >95%, e khethoa ke SDS-PAGE |
| Tlhahiso ea Buffer | 20 mM PB, 150 mM NaCl, 0.1% Proclin 300,pH7.4 |
| Polokelo | E boloke tlas'a maemo a nyopa ho -20 ℃ ho -80 ℃ ha e amoheloa. Khothalletsa ho aliquot protheine ka bongata bo nyane bakeng sa polokelo e nepahetseng. |
Tlhahlobo ea Papiso
Lintlha tsa Odara
| Lebitso la Sehlahiswa | Katse.Che | ID ea Clone |
| PGI | AB0005-1 | 1C1-3 |
| AB0005-2 | 1E3-1 | |
| AB0005-3 | 1G7-3 |
Tlhokomeliso: Li-bioantibody li ka ikamahanya le maemo ho latela tlhoko ea hau.
Litlhaloso
1.Sipponen P , Ranta P , Helske T , et al.Maemo a serum a amidated gastrin-17 le pepsinogen I ho atrophic gastritis: thuto ea ho laola linyeoe tsa tlhokomeliso.[J].Scandinavian Journal of Gastroenterology, 2002, 37 (7): 785-791.
2.Mangla JC , Schenk EA , Desbaillets L , et al.Pepsin secretion, pepsinogen, le gastrin ho Barrett's esophagus'.Litšobotsi tsa bongaka le tsa morphological[J].Gastroenterology, 1976, 70 (5 PT.1): 669-676.
