Anti- human IGFBP-1 Antibody, Mouse Monoclonal
Lintlha tsa sehlahisoa
Lintlha tse akaretsang
IGFBP1, e tsejoang hape e le IGFBP-1 le insulin-like growth factor-binding protein 1, ke setho sa insulin-like growth factor-binding protheine family.Liprotheine tse tlamang tsa IGF (IGFBPs) ke liprotheine tsa 24 ho isa ho 45 kDa.Li-IGFBP tse tšeletseng kaofela li arolelana homology ea 50% 'me li na le likamano tse tlamang bakeng sa IGF-I le IGF-II ka tatellano ea boholo bo lekanang le ea li-ligand bakeng sa IGF-IR.Liprotheine tse tlamang IGF li lelefatsa halofo ea bophelo ba li-IGF mme li bonts'itsoe hore li thibela kapa li susumetsa litlamorao tsa kholo ea li-IGF ho setso sa lisele.Ba fetola tšebelisano ea li-IGF le li-receptor tsa bona tsa sele.IGFBP1 e na le IGFBP domain le thyroglobulin type-I domain.E tlama lintlha tse peli tsa kholo ea insulin-joaloka insulin (IGFs) I le II mme e potoloha ka plasma.Ho tlamaha ha protheine ena ho lelefatsa halofo ea bophelo ba li-IGF le ho fetola tšebelisano ea bona le li-receptor tsa cell surface.
Thepa
| Keletso ea para | CLIA (Tlhapa-Tshireletso): 4H6-2 ~ 4C2-3 4H6-2 ~ 2H11-1 |
| Bohloeki | >95% joalo ka ha ho khethoa ke SDS-PAGE. |
| Tlhahiso ea Buffer | 20 mM PB, 150 mM NaCl, 0.1% Proclin 300,pH7.4 |
| Polokelo | E boloke tlas'a maemo a nyopa ho -20 ℃ ho -80 ℃ ha e amoheloa. Khothalletsa ho aliquot protheine ka bongata bo nyane bakeng sa polokelo e nepahetseng. |
Papiso ea Tlholisano
| Bioantibody | Nyeoe e hlahlobiloeng ke Clinically | Kakaretso | |
| E ntle | E mpe | ||
| E ntle | 35 | 0 | 35 |
| E mpe | 1 | 87 | 88 |
| Kakaretso | 36 | 87 | 123 |
| Tse khethehileng | 100% | ||
| Kutloisiso | 97% | ||
Lintlha tsa Odara
| Lebitso la Sehlahiswa | Katse.Che | ID ea Clone |
| IGFBP-1 | AB0028-1 | 4H6-2 |
| AB0028-2 | 4C2-3 | |
| AB0028-3 | 2H11-1 | |
| AB0028-4 | 3G12-11 |
Tlhokomeliso: Li-bioantibody li ka ikamahanya le maemo ho latela tlhoko ea hau.
Litlhaloso
1.Rutanen EM .Ntho ea kholo ea insulin e tlamang protheine 1: US 1996.
2.Harman, S, Mitchell, le ba bang.Maemo a Serum a Insulin-Like Growth Factor I (IGF-I), IGF-II, IGF-Binding Protein-3, le Prostate-Specific Antigen e le Predictors of Clinical Prostate Cancer[J].Journal of Clinical Endocrinology & Metabolism, 2000.
