Anti-human PLGF Antibody, Mouse Monoclonal
Lintlha tsa sehlahisoa
Lintlha tse akaretsang
Preeclampsia (PE) ke bothata bo tebileng ba bokhachane bo khetholloang ke khatello ea mali le proteinuria ka mor'a libeke tse 20 tsa boimana.Preeclampsia e hlaha ho 3-5% ea bakhachane 'me e baka mafu a mangata a bakhachane le lesea kapa masea le mafu.Lipontšo tsa kliniki li ka fapana ho tloha ho mefuta e bonolo ho ea ho e matla;preeclampsia e ntse e le e 'ngoe ea lisosa tse ka sehloohong tsa ho kula le lefu la lesea le lesea.
Preeclampsia e bonahala e bakoa ke ho lokolloa ha lintlha tsa angiogenic ho tloha placenta e bakang ho se sebetse ha endothelial.Maemo a serum a PlGF (placental growth factor) le sFlt-1 (soluble fms-joaloka tyrosine kinase‑1, eo hape e tsejoang e le soluble VEGF receptor‑1) a fetoloa ho basali ba nang le preeclampsia.Ho feta moo, maemo a potolohang a PlGF le sFlt-1 a ka khetholla boimana bo tloaelehileng ho tsoa ho preeclampsia le pele matšoao a kliniki a hlaha.Nakong ea bokhachane bo tloaelehileng, pro-angiogenic factor PlGF e eketseha nakong ea li-trimester tse peli tsa pele 'me e fokotseha ha boimana bo ntse bo tsoela pele ho fihlela nako e telele.Ka lehlakoreng le leng, maemo a anti-angiogenic factor sFlt-1 a lula a tsitsitse nakong ea pele le bohareng ba boimana 'me a eketseha butle ho fihlela nako e fihla.Ho basali ba nang le preeclampsia, maemo a sFlt-1 a fumanoe a phahame mme maemo a PlGF a fumanoe a le tlase ho feta nakong ea bokhachane bo tloaelehileng.
Thepa
| Keletso ea para | CLIA (Tlhapa-Tshireletso): 7G1-2 ~ 5D9-3 5D9-3 ~ 7G1-2 |
| Bohloeki | >95% joalo ka ha ho khethoa ke SDS-PAGE. |
| Tlhahiso ea Buffer | PBS, pH7.4. |
| Polokelo | E boloke tlas'a maemo a nyopa ho -20 ℃ ho -80 ℃ ha e amoheloa. Khothalletsa ho aliquot protheine ka bongata bo nyane bakeng sa polokelo e nepahetseng. |
Papiso ea Tlholisano
Lintlha tsa Odara
| Lebitso la Sehlahiswa | Katse.Che | ID ea Clone |
| PLGF | AB0036-1 | 7G1-2 |
| AB0036-2 | 5D9-3 | |
| AB0036-3 | 5G7-1 |
Tlhokomeliso: Li-bioantibody li ka ikamahanya le maemo ho latela tlhoko ea hau.
Litlhaloso
1.Brown MA, Lindheimer MD, de Swiet M, et al.Ho hlophisoa le ho hlahlojoa ha mathata a khatello ea mali nakong ea bokhachane: polelo e tsoang ho Mokhatlo oa Machaba oa Thuto ea Hypertension ka Boimana (ISSHP).Bokhachane ba Hypertens 2001;20(1):IX-XIV.
2.Uzan J, Carbonnel M, Piconne O, et al.Pre-eclampsia: pathophysiology, tlhahlobo le taolo.Vasc Health Risk Manag 2011; 7:467-474.
