Anti-human GDF15 Antibody, Mouse Monoclonal
Lintlha tsa sehlahisoa
Lintlha tse akaretsang
Growth-differentiation factor 15 (GDF15), eo hape e tsejoang e le MIC-1, ke setho se patiloeng sa phetoho ea kholo (TGF) -β superfamily, e le buka e ncha ea antihypertrophic regulatory factor in heart.GDF-15 / GDF15 ha e hlalosoe ka pelong e tloaelehileng ea batho ba baholo empa e susumetsoa ho latela maemo a khothalletsang hypertrophy le dilated cardiomyopathy 'me e hlahisoa haholo sebeteng.GDF-15 / GDF15 e na le karolo ea ho laola mekhoa ea ho ruruha le ea apoptotic ka har'a lisele tse lemetseng le nakong ea ts'ebetso ea mafu.GDF-15 / GDF15 e entsoe e le limolek'hule tse tlang pele tse sebetsoang sebakeng sa dibasic cleavage ho lokolla libaka tsa C-terminal tse nang le sebopeho sa li-cysteine tse 7 tse bolokiloeng protheineng e holileng.GDF-15 / GDF15 overexpression e hlahang karolong e atolositsoeng ea erythroid e kenya letsoho ho tlatseleng ha tšepe ho li-syndromes tsa thalassemia ka ho thibela polelo ea hepcidin.
Thepa
| Keletso ea para | CLIA (Tlhapa-Tshireletso): 23F1-5 ~ 6C1-9 23F1-5 ~ 3A2-1 |
| Bohloeki | >95%, e khethoa ke SDS-PAGE |
| Tlhahiso ea Buffer | PBS, pH7.4. |
| Polokelo | E boloke tlas'a maemo a nyopa ho -20 ℃ ho -80 ℃ ha e amoheloa. Khothalletsa ho aliquot protheine ka bongata bo nyane bakeng sa polokelo e nepahetseng. |
Papiso ea Tlholisano
Lintlha tsa Odara
| Lebitso la Sehlahiswa | Katse.Che | ID ea Clone |
| GDF-15 | AB0038-1 | 3A2-1 |
| AB0038-2 | 23F1-5 | |
| AB0038-3 | 6C1-9 | |
| AB0038-4 | 4D5-8 |
Tlhokomeliso: Li-bioantibody li ka ikamahanya le maemo ho latela tlhoko ea hau.
Litlhaloso
1.Wollert KC , Kempf T , Peter T , et al.Bohlokoa ba Prognostic of Growth-Differentiation Factor-15 ho Bakuli ba nang le Non-ST-Elevation Acute Coronary Syndrome[J].Ho potoloha, 2007, 115 (8): 962-971.
2.Kempf T , Haehling SV , Peter T , et al.Tšebeliso e nepahetseng ea phapang ea kholo-15 ho bakuli ba nang le lefu la pelo le sa foleng.[J].Journal ea American College of Cardiology, 2007, 50 (11): 1054-1060.
