Anti-human Her2 Antibody, Mouse Monoclonal
Lintlha tsa sehlahisoa
Lintlha tse akaretsang
Human epidermal growth factor receptor 2 (HER2), e tsejoang hape e le ErbB2, NEU, le CD340, ke mofuta oa I membrane glycoprotein 'me ke oa lelapa la epidermal growth factor (EGF) receptor.Protheine ea HER2 ha e khone ho tlama lintlha tsa kholo ka lebaka la ho haella ha sebaka sa eona se tlamang ligand le se ikemetseng ka mokhoa o ikemetseng.Leha ho le joalo, HER2 e etsa heterodimer e nang le litho tse ling tsa malapa a li-receptor tsa EGF tse nang le ligand, kahoo e tsitsisa ligand tlamang le ho ntlafatsa ts'ebetso ea kinase-mediated ea limolek'hule tse tlaase.HER2 e bapala karolo ea bohlokoa ntlafatsong, ho ata ha lisele le ho arola.Liphatsa tsa lefutso tsa HER2 li tlalehoa hore li amahanngoa le bofokoli le bofokoli bo bobe ba kankere e mengata, ho akarelletsa le matsoele, prostate, ovarian, kankere ea matšoafo joalo-joalo.
Thepa
| Keletso ea para | CLIA (Tlhapa-Tshireletso): 14-2 ~ 15-6 15-6 ~ 2-10 |
| Bohloeki | >95%, e khethoa ke SDS-PAGE |
| Tlhahiso ea Buffer | PBS, pH7.4. |
| Polokelo | E boloke tlas'a maemo a nyopa ho -20 ℃ ho -80 ℃ ha e amoheloa. Khothalletsa ho aliquot protheine ka bongata bo nyane bakeng sa polokelo e nepahetseng. |
Lintlha tsa Odara
| Lebitso la Sehlahiswa | Katse.Che | ID ea Clone |
| Hae2 | AB0078-1 | 14-2 |
| AB0078-2 | 15-6 | |
| AB0078-3 | 2-10 |
Tlhokomeliso: Li-bioantibody li ka ikamahanya le maemo ho latela tlhoko ea hau.
Litlhaloso
1.Krawczyk N, le ba bang.(2009) boemo ba HER2 ho lisele tsa tumor tse sa khaotseng ka mor'a phekolo ea adjuvant li ka fapana le boemo ba pele ba HER2 ho hlahala ea mantlha.Res ea Anticancer.29(10): 4019-24.
