Lintlha tse akaretsang
Hormone ea thobalano e tlamang globulin (SHBG) ke glycoprotein e ka bang 80-100 kDa;e na le kamano e phahameng bakeng sa lihomone tsa 17 beta-hydroxysteroid tse kang testosterone le estradiol.SHBG
Ho tsepamisa mohopolo ka har'a plasma ho laoloa ke, har'a tse ling, ho leka-lekana ha androgen/estrogen, lihomone tsa qoqotho, insulin le lintlha tsa lijo.Ke protheine ea bohlokoa ka ho fetisisa ea lipalangoang bakeng sa li-estrogen le li-androgens maling a peripheral.Khatiso ea SHBG ke ntlha e ka sehloohong e laolang kabo ea tsona lipakeng tsa linaha tse se nang liprotheine le tse lokolohileng.Litekanyetso tsa plasma SHBG li
angoa ke mafu a mangata a fapaneng, litekanyetso tse phahameng li fumanoa ka hyperthyroidism, hypogonadism, androgen ho se nahanele le sebete sa sebete ho banna.Maemo a tlase a fumanoa ho myxoedema, hyperprolactinemia le syndromes ea ts'ebetso e feteletseng ea androgen.Tekanyo ea SHBG e thusa tlhahlobo ea mathata a bobebe a metabolism ea androgen mme e thusa ho tsebahatsa basali ba nang le hirsutism bao ho ka etsahalang hore ba arabele kalafo ea estrogen.
Keletso ea para | CLIA (Tlhapa-Tshireletso): 3E10-1 ~ 3A10-5 3A10-5 ~ 3D8-2 |
Bohloeki | >95%, e khethoa ke SDS-PAGE |
Tlhahiso ea Buffer | PBS, pH7.4. |
Polokelo | E boloke tlas'a maemo a nyopa ho -20 ℃ ho -80 ℃ ha e amoheloa. Khothalletsa ho aliquot protheine ka bongata bo nyane bakeng sa polokelo e nepahetseng. |
Lebitso la Sehlahiswa | Katse.Che | ID ea Clone |
SHBG | AB0030-1 | 3A10-5 |
AB0030-2 | 3E10-1 | |
AB0030-3 | 3D8-2 |
Tlhokomeliso: Li-bioantibody li ka ikamahanya le maemo ho latela tlhoko ea hau.
1. Selby C. Hormone ea thobalano e tlamang globulin: tšimoloho, mosebetsi le bohlokoa ba kliniki.Ann Clin Biochem 1990; 27: 532-541.
2. Pugeat M, Crave JC, Tourniare J, et al.Tšebeliso ea bongaka ea lihomone tsa thobalano tse tlamang tekanyo ea globulin.Horm Res 1996;45(3-5):148-155.