Lintlha tse akaretsang
Hormone ea ho hōla (GH) kapa somatotropin, e tsejoang hape e le hormone ea ho hōla ha motho (hGH kapa HGH), ke hormone ea peptide e susumetsang khōlo, ho hlahisa lisele, le ho tsosolosoa ha lisele ho batho le liphoofolo tse ling.Ka hona e bohlokoa tsoelo-peleng ea batho.GH e boetse e susumetsa tlhahiso ea IGF-1 mme e eketsa khatello ea tsoekere le li-acids tse sa lefelloeng tsa mafura.Ke mofuta oa mitogen e khethehileng feela ho li-receptors tsa mefuta e itseng ea lisele.GH ke 191-amino acid, polypeptide e le 'ngoe ea ketane e entsoeng, e bolokoa le ho patoa ke lisele tsa somatotropic ka har'a mapheo a ka morao a lesela le ka pele la pituitary.
Liteko tsa GH li sebelisetsoa ho hlahloba mathata a GH, ho kenyelletsa:
★ khaello ea GH.Ho bana, GH e bohlokoa bakeng sa khōlo e tloaelehileng le tsoelo-pele.Ho haella ha GH ho ka etsa hore ngoana a hōle butle 'me a be khutšoanyane ho feta bana ba lilemo tse tšoanang.Ho batho ba baholo, khaello ea GH e ka lebisa ho fokotseha ha masapo le ho fokotsa mesifa ea mesifa.
★ Gigantism.Ena ke bothata bo sa tloaelehang ba bongoaneng bo etsang hore 'mele o hlahise GH e ngata haholo.Bana ba nang le gigantism ba telele haholo bakeng sa lilemo tsa bona mme ba na le matsoho le maoto a maholo.
★ Acromegaly.Bothata bona, bo amang batho ba baholo, bo etsa hore ’mele o hlahise hormone e ngata haholo ea ho hōla.Batho ba baholo ba nang le acromegaly ba na le masapo a maholo ho feta a tloaelehileng le matsoho a atolositsoeng, maoto le likarolo tsa sefahleho.
Keletso ea para | CLIA (Tlhapa-Tshireletso): 7F5-2 ~ 8C7-10 |
Bohloeki | / |
Tlhahiso ea Buffer | / |
Polokelo | E boloke tlas'a maemo a nyopa ho -20 ℃ ho -80 ℃ ha e amoheloa. Khothalletsa ho aliquot protheine ka bongata bo nyane bakeng sa polokelo e nepahetseng. |
Lebitso la Sehlahiswa | Katse.Che | ID ea Clone |
GH | AB0077-1 | 7F5-2 |
AB0077-2 | 8C7-10 | |
AB0077-3 | 2A4-1 | |
AB0077-4 | 2E12-6 | |
AB0077-5 | 6F11-8 |
Tlhokomeliso: Li-bioantibody li ka ikamahanya le maemo ho latela tlhoko ea hau.
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2. Greenwood FC, Landon J (April 1966)."Ho hlahisa li-hormone tsa kholo ho arabela khatello ea kelello ho motho".Tlhaho.210 (5035): 540–1.Khouto:1966Natur.210..540G.doi:10.1038/210540a0.PMID 5960526. S2CID 1829264.