Anti- human TIMP1 Antibody, Mouse Monoclonal
Lintlha tsa sehlahisoa
Lintlha tse akaretsang
TIMP metallopeptidase inhibitor 1, eo hape e tsejoang e le TIMP-1/TIMP1, Collagenase inhibitor 16C8 fibroblast Erythroid-potentiating activity, TPA-S1TPA-induced proteinTissue inhibitor of metalloproteinases 1, ke tlhaho ea tlhaho inhibitors ea metalloptises pedases (MMPP) e ameha ho senyeha ha matrix a extracellular.TIMP-1/TIMP1 e fumaneha ka har'a litho tsa lesea le batho ba baholo.Maemo a phahameng ka ho fetisisa a fumanoa masapong, matšoafong, ovary le popelong.E rarahane ka metalloproteinase 'me e e etsa hore e se ke ea etsolloa ka ho tlama cofactor ea tsona ea catalytic zinc.TIMP-1/TIMP1 e sebelisana le erythropoiesis in vitro;empa, ho fapana le IL-3, e itšetlehile ka mefuta-futa, e susumetsang khōlo le phapang ea li-progenitors tsa erythroid feela tsa batho le murine.Ntle le karolo ea eona ea thibelo khahlanong le boholo ba li-MMP tse tsejoang, protheine e khona ho khothalletsa ho ata ha lisele ka mefuta e mengata ea lisele, hape e ka 'na ea e-ba le mosebetsi o khahlanong le apoptotic.Phetolelo ea mofuta ona oa encoding ea protheine e bonolo haholo ho arabela li-cytokine le lihomone tse ngata.Ho feta moo, polelo e tsoang ho tse ling empa e se li-chromosome tsohle tse sa sebetseng tsa X e fana ka maikutlo a hore ho se sebetse hona ha liphatsa tsa lefutso ke polymorphic ho basali ba batho.Mofuta ona oa khouto o fumaneha ka har'a intron 6 ea liphatsa tsa lefutso tsa synapsin I 'me o ngotsoe ka lehlakoreng le leng.E rarahane ka metalloproteinase 'me e e etsa hore e se ke ea etsolloa ka ho tlama cofactor ea tsona ea catalytic zinc.TIMP-1/TIMP1 e tsejoa e sebetsa ho MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13 le MMP-16.
Thepa
| Keletso ea para | CLIA (Tlhapa-Tshireletso): 1D5-5 ~ 3G11-6 1D12-2 ~ 1G3-7 |
| Bohloeki | >95% joalo ka ha ho khethoa ke SDS-PAGE. |
| Tlhahiso ea Buffer | PBS, pH7.4. |
| Polokelo | E boloke tlas'a maemo a nyopa ho -20 ℃ ho -80 ℃ ha e amoheloa. Khothalletsa ho aliquot protheine ka bongata bo nyane bakeng sa polokelo e nepahetseng. |
Papiso ea Tlholisano
Lintlha tsa Odara
| Lebitso la Sehlahiswa | Katse.Che | ID ea Clone |
| TIMP1 | AB0034-1 | 1D5-5 |
| AB0034-2 | 1D12-2 | |
| AB0034-3 | 1G3-7 | |
| AB0034-4 | 3G11-6 |
Tlhokomeliso: Li-bioantibody li ka ikamahanya le maemo ho latela tlhoko ea hau.
Litlhaloso
1.Barylski M , Kowalczyk E , Szadkowska I , et al.[Tissue inhibitor of metalloproteinase[J].Polski Merkuriusz Lekarski Organ Polskiego Towarzystwa Lekarskiego, 2011, 30(178):246-8.
2.Hayakawa T , Yamashita K , Tanzawa K , et al.Ts'ebetso e khothalletsang kholo ea lisele tse thibelang likokoana-hloko tsa metalloproteinases-1 (TIMP-1) bakeng sa lisele tse ngata tse fapaneng Ntho e ka 'nang ea e-ba e ncha ea khōlo ea serum [J].Mangolo a FEBS, 1992, 298.
3.Haider DG , Karin S , Gerhard P , et al.Serum retinol- tlamang protheine ea 4 e fokotsehile ka mor'a ho lahleheloa ke boima ba 'mele ho batho ba batenya haholo.[J].Journal of Clinical Endocrinology & Metabolism (3): 1168-71.
