Lintlha tse akaretsang
S100B ke protheine e tlamang k'halsiamo, e tsoang ho li-astrocyte.Ke protheine e nyane ea dimeric cytosolic (21 kDa) e nang le liketane tsa ββ kapa αβ.S100B e ameha mesebetsing e fapaneng ea taolo ea intracellular le extracellular.
Lilemong tse leshome tse fetileng, S100B e hlahile e le sekhechana sa "biomarker" sa "blood-brain barrier" (BBB) le kotsi ea CNS.Maemo a phahameng a S100B a bonahatsa ka nepo boteng ba maemo a neuropathological ho kenyelletsa le kotsi e bohloko ea hlooho le mafu a neurodegenerative.Maemo a tloaelehileng a S100B ha a kenyelle mafu a maholo a CNS.Serum S100B e boetse e tlalehoa e le letšoao le molemo bakeng sa ho lemoha metastase ea melanoma le mathata a boko ka lebaka la ho tsoa kotsi ea hlooho, opereishene ea pelo le stroke se matla.
Keletso ea para | CLIA (Tlhapa-Tshireletso): 5H2-3 ~ 22G7-5 22G7-5 ~ 5H2-3 |
Bohloeki | >95% joalo ka ha ho khethoa ke SDS-PAGE. |
Tlhahiso ea Buffer | 20 mM PB, 150 mM NaCl, 0.1% Proclin 300,pH7.4 |
Polokelo | E boloke tlas'a maemo a nyopa ho -20 ℃ ho -80 ℃ ha e amoheloa. Khothalletsa ho aliquot protheine ka bongata bo nyane bakeng sa polokelo e nepahetseng. |
Lebitso la Sehlahiswa | Katse.Che | ID ea Clone |
s100 β | AB0061-1 | 5H2-3 |
AB0061-2 | 22G7-5 | |
AB0061-3 | 21A6-1 |
Tlhokomeliso: Li-bioantibody li ka ikamahanya le maemo ho latela tlhoko ea hau.
1. Ostendorp T , Leclerc E , Galicet A , et al.Lintlha tsa sebopeho le ts'ebetso ea ts'ebetso ea RAGE ka multimeric S100B[J].Koranta ea EMBO, 2007, 26 (16): 3868-3878.
2. R, D, Rothoerl, le ba bang.Maemo a phahameng a serum S100B bakeng sa bakuli ba tsielehileng ba se nang likotsi tsa hlooho.[J].Neurosurgery, 2001.