Lintlha tse akaretsang
Interleukin-6 (IL-6) ke α-helical cytokine e sebetsang ka bongata e laolang kholo ea lisele le ho arohana ha lisele tse fapa-fapaneng, tse tsejoang ka ho khetheha bakeng sa karolo ea eona ea ho itšireletsa mafung le liketsong tse matla tsa mohato.Protheine ea IL-6 e hlahisoa ke mefuta e fapaneng ea lisele tse kenyelletsang lisele tsa T le macrophages joalo ka molek'hule ea phosphorylated le ea glycosylated.E etsa liketso ka receptor ea eona ea heterodimeric e entsoeng ka IL-6R e hlokang sebaka sa tyrosine / kinase 'me e tlama IL-6 ka kamano e tlaase,' me e hlahisoa hohle ka glycoprotein 130 (gp130) e tlamang IL-6.IL-6R e rarahaneng e nang le kamano e phahameng 'me kahoo e fetisa lipontšo.IL-6 e boetse e ameha ho hematopoiesis, metabolism ea masapo, le tsoelo-pele ea mofetše, 'me e hlalositsoe e le karolo ea bohlokoa ea ho tsamaisa phetoho ho tloha ka tlhaho ho ea ho itšireletsa mafung.
Keletso ea para | CLIA (Tlhapa-Tshireletso): 1B1-4 ~ 2E4-1 2E4-1 ~ 1B1-4 |
Bohloeki | >95%, e khethoa ke SDS-PAGE |
Tlhahiso ea Buffer | PBS, pH7.4. |
Polokelo | E boloke tlas'a maemo a nyopa ho -20 ℃ ho -80 ℃ ha e amoheloa. Khothalletsa ho aliquot protheine ka bongata bo nyane bakeng sa polokelo e nepahetseng. |
Lebitso la Sehlahiswa | Katse.Che | ID ea Clone |
IL6 | AB0001-1 | 1B1-4 |
AB0001-2 | 2E4-1 | |
AB0001-3 | 2C3-1 |
Tlhokomeliso: Li-bioantibody li ka ikamahanya le maemo ho latela tlhoko ea hau.
1.Zhong Z, Darnell ZW, Jr. Stat3: setho sa lelapa sa STAT se sebelisitsoeng ke tyrosine phosphorylation ho arabela ho epidermal growth factor le interleukin-6 [J].Saense, 1994.
2.J, Bauer, F, le ba bang.Interleukin-6 ka meriana ea bongaka[J].Annals of Hematology, 1991.